Notre Dame is coming off a big win at Duke. They face off versus another ranked opponent away from home in Louisville. Notre Dame is averaging 461 yards per game and they are facing off versus a Louisville defense that gives up 327 yards per game. Notre Dame’s defense has not looked as excellent in recent weeks, but we would like them to shut down this Cardinal’s offense. Louisville is only converting on 40 percent on their third downs and they have allowed three sacks in 2 games at home versus very subpar teams. We like Notre Dame to cover the -6.5 point spread away from home.
Our Pick: Notre Dame -6.5
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